Fix Zithro (Bird Zithro) Azithromycin 250mg 12/30ct Fish & Bird Antibiotic

Fix Zithro (Bird Zithro) Azithromycin Tablets - 250 mg

Fix Zithro 250 mg is a trusted, pharmaceutical-grade, broad-spectrum fish and bird antibiotic for ornamental aquarium fish and non-food pet birds. Often called Bird Zithro or Fish Zithro in the hobby community, Fix Zithro serves as a reliable online alternative to discontinued Thomas Labs Bird Zithro, Fish Zithro and Aqua Zithro 250 mg products.

This over-the-counter (OTC) azithromycin tablet from the Aqua Soma Labs Fix range helps manage common problems such as fin and tail rot, columnaris, gill disease, bacterial hemorrhagic septicemia, and other bacterial infections in freshwater and saltwater aquariums. Bird keepers also use it, under veterinary guidance, as a bird azithromycin option for mild upper respiratory tract infections (URI), suspected Mycoplasma issues, or conditions like chlamydia psittaci (psittacosis / parrot fever) in pigeons and other pet birds.

Azithromycin is a macrolide antibiotic that works by interfering with bacterial protein synthesis, which helps slow or stop the growth of susceptible bacteria in the gills, skin and respiratory tract. When used as directed in fish or birds, azithromycin can be part of a broader management plan that also includes good husbandry, clean water and appropriate nutrition.

Fix Zithro from Aqua Soma Labs supplies 250 mg azithromycin per tablet and is available to buy online in bottles of 12 or 30 tablets with fresh expiration dates. This gives hobbyists flexible options, whether they maintain a single hospital tank, multiple community aquariums, or need effective flock treatment and loft management for a busy aviary.

Use Fix Zithro when you notice early signs of bacterial stress such as stubborn fin rot, clamped or frayed fins, red or cloudy patches on the body, pop-eye (exophthalmia), gill irritation, gill flukes secondary infections, listlessness or a persistent loss of appetite in fish. For birds, watch for sneezing, nasal discharge, swollen eyes / sinus infections, ruffled feathers or reduced activity. Addressing potential bacterial issues early with azithromycin treatment, together with good water quality, suitable housing and advice from an aquatic or avian professional when available, helps your fish and birds maintain a stable, healthy aquarium or aviary.

Order online and enjoy same-day dispatch on orders placed before 1:30 p.m. CT, Monday through Friday. Fix Zithro ships directly from our U.S. warehouse via USPS or UPS.

Important Notice: This product is intended for aquarium and ornamental fish and pet birds only. It is not for human consumption or for animals used for food. We do not sell or recommend this product for human use.

Bird Zithro vs Fix Zithro: What Changed?

If you previously purchased Thomas Labs Bird Zithro, Fish Zithro or Aqua Zithro, here is what has changed and what remains the same:

Benefits of Fix Zithro for Fish & Birds

• Broad-Spectrum Bacterial Support

  Fix Zithro provides broad-spectrum azithromycin coverage for ornamental fish and non-food pet birds. It helps manage common problems such as fin and tail rot, columnaris, gill disease, and early respiratory signs or the ornithosis complex in birds when used as directed.

• No Veterinary Prescription Required

  Fix Zithro is available over the counter for aquarium and avian use, so you can start treatment promptly without waiting for a prescription. For birds, professional veterinary guidance is still strongly recommended to determine the correct dose and duration.

• Helps With Internal and External Infections

  Azithromycin in Fix Zithro can be used for skin lesions, ulcers, fin damage and internal infections in a hospital tank, as well as part of a treatment plan for mild respiratory or Mycoplasma-related concerns in pet birds.

• Consistent 250 mg Tablets

  Each tablet delivers a reliable 250 mg azithromycin dose, making it easier to scale treatment from a single betta or quarantine tank up to larger community aquariums, lofts or aviaries without complicated calculations.

• Easy to Administer

  These crushable tablets are easy to mix and can be dissolved directly in aquarium water or mixed with soft food, providing flexible options for shy, stressed or hard-to-handle fish and birds while minimizing handling and extra stress.

• Versatile for Freshwater, Saltwater & Aviary Setups

  Hobbyists reach for Fix Zithro as their trusted choice in both freshwater and marine systems, and as a convenient option for pigeons and other ornamental birds kept in lofts, cages or aviaries.

• Ideal for Hospital Tanks and Quarantine

  Using Fix Zithro in a separate hospital tank or treatment cage helps protect the main aquarium's biofilter and reduces unnecessary exposure of healthy tank mates or flock members while you focus treatment where it is needed most.

Dosage Guidelines & Instructions

Directions for Use:

1. Set Up a Separate Treatment Area

   Move affected fish to a dedicated hospital tank and, where practical, house birds needing treatment in a small treatment cage. This helps protect healthy tank mates or flock members and lets you control dosing more precisely.

2. Dose for Fish Aquariums

   Dissolve one 250 mg tablet per 10 gallons (38 L) of water in the hospital tank. Mix the tablet in a small cup of aquarium water first, then distribute it evenly around the tank. Repeat the dose every 24 hours for 5-7 days while closely monitoring water quality and fish behavior. This is the standard dosage for fish unless your aquatic veterinarian advises otherwise.

3. Use in Pet Birds (Under Veterinary Guidance)

   Only administer Fix Zithro to pigeons and other pet birds under the direction of an avian veterinarian. Your vet can advise you on the correct mg-per-kg dose, frequency and duration. Tablets may be given whole, split, or crushed and mixed into soft food or drinking water exactly as instructed.

4. Maintain Water Quality & Complete the Course

   Perform partial water changes as needed between doses to keep ammonia and nitrite low and ensure good aeration in the hospital tank. Continue treatment for the full recommended course even if fish or birds appear better; stopping early can allow symptoms to return. If there is no improvement after several days, or if signs worsen, consult an aquatic or avian professional.

Pro Tip: Always quarantine infected fish and birds away from healthy companions during treatment to reduce stress and help prevent the spread of disease. A small, dedicated hospital tank with a heater, air stone and no substrate makes dosing and water changes easier.

How This Medication Works

• Active ingredient: Azithromycin (250 mg per tablet)

  Azithromycin is a macrolide antibiotic that interferes with bacterial protein synthesis, helping slow or stop the growth of susceptible bacteria in the gills, skin and respiratory tract of ornamental fish and non-food pet birds.

• Inactive ingredients

  Tablet excipients that help keep the azithromycin stable on the shelf and allow the tablet to disperse and dissolve properly when added to aquarium water or mixed with soft food.

Shipping & Returns

Frequently Asked Questions

More Fish & Bird Antibiotics